Children < 12 years
Second-line treatment

Warning: Array to string conversion in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Undefined variable $Array in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Trying to access array offset on null in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Array to string conversion in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Undefined variable $Array in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Trying to access array offset on null in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Array to string conversion in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Undefined variable $Array in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37

Warning: Trying to access array offset on null in /home/clients/d0fa621b06e69d3a150fb7f06cec713f/vhost/sfdermato.org/reco/dev/APP/worker/locale.php on line 37
19/01/2026

In case of failure with single doses of second-generation anti-H1 antihistamines

Gradually increase the dose of anti-H1 antihistamines up to 4 doses per day.

As a second-line treatment, the WG instead recommends multiple doses of rupatadine (no longer available in oral solution since 2018) or desloratadine; these 2 anti-H1 antihistamines have been studied at double, triple and quadruple doses, with a “demonstration” of efficacy and good tolerance in 46 patients.

Delays vary from 1 week to 1 month between each dose increase in the literature.

➜