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Centre of Evidence of Dermatology Best practice guidelines

Guidelines classic scabies: in children < 15kg, pregnant or breastfeeding women Updated on january 2024

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Clinical scenario No. 1/3 - Scabies, pediatric clinical case

Back to decision-making tree Print last updated on 06/06/2024

Presentation 1/3, initial case :

What treatment and management are needed?

See propositions

×

Therapeutic treatment suggestions

Marie: 3 years, 13kg

Local treatment:
  • permethrin 5% cream1
  • or
  • benzyl benzoate 10% skin emulsion2
Related environmental measures3
Simultaneous treatment for the whole family
Interrupt communal activities (school) for 3 days

Louise: 18 months, 10kg

Local treatment:
  • permethrin 5% cream,1 recommended for infants (< 1 year), for damaged skin or if the face is affected, to avoid irritating the skin and mucous membranes
  • or
  • benzyl benzoate 10% skin emulsion4
Related environmental measures3
Simultaneous treatment for the whole family
Interrupt communal activities (school) for 3 days

Ninon: 6 weeks, 4.5kg

Consider hospital treatment
Outpatient or inpatient depending on the context
Local treatment:
Permethrin 5% cream1
Related environmental measures3
Simultaneous treatment for the whole family

Howto

  1. Apply a thin layer over the entire body in the evening. Leave on overnight (minimum 8 hours) and rinse off in the morning. Apply on D0 and reapply between D8 and D14.
  2. Two successive full-body applications (or one application depending on tolerance). Leave on for 24 hours then rinse off. Apply on D0 and reapply between D8 and D14.
  3. Decontamination of bedding and clothing by machine washing at 50°C or 3 days in a sealed bag, treatment of mattress, furniture and car seats with anti-parasitic spray.
  4. One full-body application, reduce time on skin to 12 or even 6 hours according to tolerance, then rinse off. Apply on D0 and reapply between

Step 2/3

The family returns 3 months later with the same clinical picture and a recurrence is confirmed.

What treatment and management are needed?

Read the proposition

×

Therapeutic treatment suggestions

If treatment failure for Marie, 3 years, 13kg

After confirming treatment failure and analysing the underlying conditions:

  • recontamination, poor compliance, intolerance of local treatment, poor clothing/bedding decontamination, subjects not all treated simultaneously, etc.
Same product or the other proposed for 1st-line local treatment:
  • permethrin 5% cream1
  • or
  • benzyl benzoate 10% skin emulsion2
  • or
  • ivermectin oral (2 doses: D0 and between D8 and D14, mid meal)
    • if compliance is doubtful, the child’s skin condition is poor or in cluster cases
    • if the child has not been to a tropical area where there is a risk of helminthiasis
Related environmental measures and simultaneous treatment for the whole family

If treatment failure for Louise, 18 months, 10kg

After confirming treatment failure and analysing the underlying conditions:

  • recontamination, poor compliance, intolerance of local treatment, poor clothing/bedding decontamination, subjects not all treated simultaneously, etc.
Same product or the other proposed for 1st-line local treatment:
  • permethrin 5% cream,1 recommended for infants (< 1 year), for damaged skin or if the face is affected, to avoid irritating the skin and mucous membranes
  • or
  • benzyl benzoate 10% skin emulsion3
  • or
  • ivermectin oral (2 doses: D0 and between D8 and D14, mid meal)
    • if compliance is doubtful, the child’s skin condition is poor or in cluster cases
    • if the child has not been to a tropical area where there is a risk of helminthiasis
Related environmental measures andsimultaneous treatment for the whole family

If treatment failure for Ninon, 6 weeks, 4.5kg

Consider hospital treatment (outpatient or inpatient depending on the context)

After confirming treatment failure and analysing the underlying conditions:

  • recontamination, poor compliance, intolerance of local treatment, poor clothing/bedding decontamination, subjects not all treated simultaneously, etc.
Same local treatment:
  • permethrin 5% cream1
Related environmental measures and simultaneous treatment for the whole family

Howto

  1. Apply a thin layer over the entire body in the evening. Leave on overnight (minimum 8 hours) and rinse off in the morning. Apply on D0 and reapply between D8 and D14.
  2. Two successive foll-body applications (or one application depending on tolerance). Leave on for 24 hours then rinse off. Apply on D0 and reapply between D8 and D14.
  3. One full-body application, reduce time on skin to 12 or even 6 hours according to tolerance, then rinse off. Apply on D0 and reapply between D8 and D14.

Step 3/3

If initially, only the parents are affected and the children show no signs of scabies, what treatment and management are needed for the 3 children contact subjects?

What is your proposition?

See proposition

×

Therapeutic treatment suggestions

Marie, 3 years, 13kg

Local treatment:
  • permethrin 5% cream1
  • or
  • benzyl benzoate 10% skin emulsion2

Louise, 18 months, 10kg

Local treatment:
  • permethrin 5% cream,1 recommended for infants (< 1 year), for damaged skin or if the face is affected, to avoid irritating the skin and mucous membranes
  • or
  • benzyl benzoate 10% skin emulsion2

Ninon, 6 weeks, 4.5kg

No systematic treatment for infants < 2 months, but reassessment at 2-3 weeks.

Associated measures

  • Related environmental measures3
  • w
  • and simultaneous treatment for the whole family

Howto

  1. Apply a thin layer over the entire body in the evening. Leave on overnight (minimum 8 hours) and rinse off in the morning. Apply on D0 and reapply between D8 and D14.
  2. One full-body application, leave on for 24 hours then rinse off (reduce time on skin to 12 or even 6 hours for infants < 2 years and according to tolerance). Apply on D0 and reapply between D8 and D14.
  3. Decontamination of bedding and clothing by machine washing at 50°C or 3 days in a sealed bag, treatment of mattress, furniture and car seats with anti-parasitic spray.
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